Catergory ARTICLES POSTED

My CV updated 4-19-2016

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My articles accepted in 3rd International Congress of Veterinary Pharmacology and Pharmaceutical Sciences and will be presented at May 25 2016, The titles are:

  •  A Comparative Study of The Pattern of Antibiotic Resistance of Bacteria Isolated From Healthy and Diarrheal Pet Feces.
  • Evaluation of The Protective Effect of The Ginger and Thyme Extract on Hemorrhagic Necrotic Enteritis With Antibiotic Therapy in Dog Animal Model.

A Comparative Study of The Pattern of Antibiotic Resistance of Bacteria Isolated From Healthy and Diarrhea Pet Feces.

Objectives: Antibiotic resistance due to the worldwide usage of antibiotics is one of the biggest failures in antibiotic treatment. The aim of this study is determine bacteria and also investigate the sensitivity and antibiotic resistance of bacteria isolated from feces of diarrheal and healthy dogs and cats in Karaj city in 2015.
Materials & Methods: In this study 50 isolateds from feces of diarrheal and 50 isolateds of healthy dogs and cats were determined. As well as the effect of oxytetracycline, azithromycin, cefixime, tetracycline, tylosin, gentamaicin, sulphadiazine, chloramphenicol antibiotics were evaluated on bacteria isolated by disc diffusion method. Campylobacter were confirmed by multiplex PCR and salmonella by PCR and using invA gene specified primers.
Results & Conclusion: Results related to studied antibiotics effects showed that all isolated bacteria were sensitive with high percentage to sulphadiazine, cefixime and tylosin. On resistance of isolated bacteria to antibiotics, they were resistant to penicillin (94 percent), chloramphenicol (62 percent), gentamaicin (45 percent), tetracycline (34 percent), oxytetracycline (25 percent) and azithromycin (15 percent). E. colli bacteria had full resistance to penicillin and azithromycin. Results were also indicated that the percentage of E. colli, pseudomonas aeruginosa, proteus, lactobacillus, clostridium perfringens in healthy dogs and cats were more than diarrheal ones. In other hand, the percentage of staphylococcus aureus, corynebacterium, salmonella and bacillus cereus in diarrheal dogs and cats were more than healthy. Also, cats given campylobacter were more than dogs.
Keywords antibiotic resistance, diarrheal, pet feces

 

Evaluation of the protective effect of the ginger and thyme extract on hemorrhagic necrotic enteritis with antibiotic therapy in dog animal model

Objectives: Increased resistance to antibiotics caused routine infection become fatal cases; and can cause influence and application failure in many modern treatments. Effectiveness of some plants with antibacterial properties as well as combining herbs with antibiotics are known to improve intestinal diseases, since ginger and thyme have antibacterial properties.
Materials & Methods: In this study were evaluated protective effect of these two plants with antibiotic therapy for treatment of hemorrhagic enteritis caused by bacteria such as E. colli, clostridium, campylobacter and salmonella. In an experiment with 50 dogs, 54 percent were with E. coli, 32 percent with salmonella, 30 percent campylobacter and 12 percent were with clostridium that meanwhile E. colli introduced as the main cause of hemorrhagic enteritis with the most prevalence. Treatment includes ginger and thyme extract and 3 types of antibiotics, including gentamicin, ceftriaxone and cefixime.
Results & Conclusion: Results showed that these two extracts showed no significant effect on bacteria growthsolely; while combination of ginger, thyme and gentamicin have a significant effect on sensitivity in E. coli, and also combination of these two extracts had more productivity effect; and associated with ceftriaxone and cefixime showed significant effects on E. coli and salmonella growth, while failed to effect on campylobacter.
Keywords: ginger and thyme extract, hemorrhagic necrotic enteritis, antibiotic therapy, dog

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